Joseph Greely, DVM
Dr. Greely's primary interests are in nonhuman primate surgery and dentistry.
Dr. Greely's primary interests are in nonhuman primate surgery and dentistry.
The field of immunometabolism has fundamentally revolutionized our understanding of the pathogenesis of infectious diseases. In a landmark study, we first report immune cells in HIV-infected volunteers utilize glucose differently from uninfected volunteers and is linked to immune dysfunctions. At the fundamental level, nutrient metabolism influences immune cell survival, differentiation and functions, and our work illuminates how HIV distorts host metabolic machineries as an immune escape mechanism.