Robert V. Blair, PhD, DVM, DACVP
Associate Professor of Pathology and Laboratory Medicine
Education & Affiliations
Research
My research is focused on studying the impact of vaping aerosol exposure on innate pulmonary defense mechanisms in a nonhuman primate model. I also have a special interest in applying artificial intelligence and computer-based methodologies to quantify histopathologic lesions to better characterize and compare animal disease models. As an ACVP Board Certified veterinary pathologist, I collaborate extensively with intramural and extramural researchers on several nonhuman primate infectious disease models including: SARS-CoV-2, SIV, CMV, Zika virus, tuberculosis, and Lyme disease. I also play a major part in the primate center's training mission by holding regular training rounds and overseeing the summer student program.
Current Funding: K01 OD032309 (PI: Blair)
Select Publication
The impact of vaping aerosol exposure on innate pulmonary defense mechanisms in nonhuman primates
Contributions
Rutkai I, Mayer MG, Hellmers LM, Ning B, Huang Z, Monjure CJ, Coyne C, Silvestri R, Golden N, Hensley K, Chandler K, Lehmicke G, Bix GJ, Maness NJ, Russell-Lodrigue K, Hu TY, Roy CJ, Blair RV, Bohm R, Doyle-Meyers LA, Rappaport J, Fischer T. Neuropathology and virus in brain of SARS-CoV-2 infected non-human primates. Nat Commun. 2022;13(1):1745. Epub 20220401. doi: 10.1038/s41467-022-29440-z. PubMed PMID: 35365631; PubMed Central PMCID: PMCPMC8975902.
Qin Z, Liu F, Blair R, Wang C, Yang H, Mudd J, Currey JM, Iwanaga N, He J, Mi R, Han K, Midkiff CC, Alam MA, Aktas BH, Heide RSV, Veazey R, Piedimonte G, Maness NJ, Ergun S, Mauvais-Jarvis F, Rappaport J, Kolls JK, Qin X. Endothelial cell infection and dysfunction, immune activation in severe COVID-19. Theranostics. 2021;11(16):8076-91. Epub 2021/08/03. doi: 10.7150/thno.61810. PubMed PMID: 34335981; PubMed Central PMCID: PMCPMC8315069.
Melton A, Doyle-Meyers LA, Blair RV, Midkiff C, Melton HJ, Russell-Lodrigue K, Aye PP, Schiro F, Fahlberg M, Szeltner D, Spencer S, Beddingfield BJ, Goff K, Golden N, Penney T, Picou B, Hensley K, Chandler KE, Plante JA, Plante KS, Weaver SC, Roy CJ, Hoxie JA, Gao H, Montefiori DC, Mankowski JL, Bohm RP, Rappaport J, Maness NJ. The pigtail macaque (Macaca nemestrina) model of COVID-19 reproduces diverse clinical outcomes and reveals new and complex signatures of disease. PLoS pathogens. 2021;17(12):e1010162. Epub 20211220. doi: 10.1371/journal.ppat.1010162. PubMed PMID: 34929014; PubMed Central PMCID: PMCPMC8722729.
Beddingfield BJ, Maness NJ, Fears AC, Rappaport J, Aye PP, Russell-Lodrigue K, Doyle-Meyers LA, Blair RV, Carias AM, Madden PJ, Redondo RL, Gao H, Montefiori D, Hope TJ, Roy CJ. Effective Prophylaxis of COVID-19 in Rhesus Macaques Using a Combination of Two Parenterally-Administered SARS-CoV-2 Neutralizing Antibodies. Frontiers in cellular and infection microbiology. 2021;11:753444. Epub 20211118. doi: 10.3389/fcimb.2021.753444. PubMed PMID: 34869063; PubMed Central PMCID: PMCPMC8637877.
