Huanbin Xu, PhD
Professor of Pathology and Laboratory Medicine
Education & Affiliations
Research
Dr. Huanbin Xu is a tenured professor in the Department of Pathology and Laboratory Medicine at the Tulane University School of Medicine. He has established a strong track record in immunology, virology, molecular biology, and related interdisciplinary fields.
Dr. Xu’s research focuses on neonatal immune development and immunosenescence, epigenetic regulation of germinal center responses in lymph nodes following vaccination, early pediatric HIV prevention strategies, viral reservoir assays, and trained innate immunity. He also investigates immunometabolic alterations and early diagnostic approaches in pediatric tuberculosis. His work has contributed significantly to the understanding of immune responses, with publications featured in The Journal of Immunology, Mucosal Immunology, and EBioMedicine, among others.
In addition to his research, Dr. Xu actively contributes to the scientific community as a reviewer for multiple NIH study sections, an ad hoc reviewer for several journals, and a member of the editorial boards of Scientific Reports and Frontiers.
Professional Awards
Award from Carol Lavin Bernick Foundation in LB Grant program, 2020
Outstanding Achievement and Commitment to Excellence In Total Competitive Research funding, Tulane University School of Medicine, 2015 and 2023
Contributions
Wang X, Vincent E, Siddiqui S, Turnbull K, Lu H, Blair R, Wu X, Watkins M, Ziani W, Shao J, Doyle-Meyers LA, Russell-Lodrigue KE, Bohm RP, Veazey RS, Xu H. Early treatment regimens achieve sustained virologic remission in infant macaques infected with SIV at birth. Nat Commun. 2022. 13 (1): 4823. PMID: 35973985
Ziani W, Shao J, Wang X, Russell-Lodrigue K, Liu Y, Montaner L, Veazey R and Xu H. Increased proviral DNA in circulating cells correlates with plasma viral rebound in simian immunodeficiency virus-infected rhesus macaques after antiretroviral therapy interruption. J Virol. 2021. DOI:10.1128/JVI.02064-20. PMID: 33408173
Xu H, Ziani, Shao JS, Doyle-Meyers LA, Russell-Lodrigue KE, Ratterree M, Veazey RS and Wang X. Impaired development and expansion of germinal center follicular T helper cells in SIV-infected neonatal macaques. J Immunol. 2018. 201(7): 1994-2003. PMID: 30104244
Xu H, Wang X, Malam N, Aye PP, Alvarez X, Lackner AA and Veazey RS. Persistent SIV infection drives differentiation, aberrant accumulation, and latent infection of germinal center follicular T helper cells. J Virol. 2015. PMID: 26608323
Xu H, Wang X, Liu DX, Rasmussen T, Lackner AA, Veazey RS. IL-17-producing innate lymphoid cells are restricted to mucosal tissues and are depleted in SIV-infected macaques. Mucosal Immunol. 2012. 5(6): 658-669. PMID: 22669579
Wang X, Mehra S, Kaushal D, Veazey RS and Xu H. Abnormal tryptophan metabolism in HIV and mycobacterium tuberculosis infection. Front Microbiol. 2021. PMID: 34262540
Xu H, Blair RV, Veazey RS, Xiaolei Wang X. Immunopathogenesis in HIV-associated Mycobacterium tuberculosis infection. Pediatric Research. 2021. doi: 10.1038/s41390-021-01393-x. PMID: 33731810
