High Containment Research Performance Core

The High Containment Research Performance Core (HCRPC) is dedicated to providing full or partial support for researchers seeking to perform BSL3 and Select Agent studies. The HCPRC provides services for bacterial/viral culture and propagation, as well as sample preparation and processing. We also offer project management assistance in study design, budgeting, and IACUC and IBC preparation. Our standard operating procedures have been thoroughly tested to ensure consistent practices and have undergone rigorous quality assurance processes to ensure reproducibility of all related activities.

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Acknowledgments

When utilizing research resources made possible by the TNPRC High Containment Research Performance Core, please cite RRID:SCR_024612. For additional information on acknowledging Tulane National Primate Research Center resources, please see here.

Analytic Services

qPCR platform for nucleic quantification, diagnostic, subgenomic N&E for SARS CoV-2

Olink Signature Q100 is our benchtop solution for researchers who want to analyze specific protein sets. It uses our proven PEA technology with a qPCR readout to measure 92 proteins per sample. It's particularly well-suited for smaller studies or when you need to validate specific findings quickly. Olink Target 96 — Olink® Olink Target 48 — Olink®

Desktop qPCR instrument
Analyzes 92 proteins per sample
Best for smaller studies or targeted validation
Quick turnaround with results in 24 hours
Uses PEA technology with qPCR readout

Olink Reveal takes things to the next level by incorporating next-generation sequencing (NGS). It can measure approximately 1,000 proteins in each sample and is especially rich in immune response and inflammation markers. Olink Reveal — Olink®

Next-generation sequencing (NGS) platform
Measures ~1,000 proteins per sample
Ideal for medium-scale studies
Enriched for immune response and inflammation markers
Uses PEA technology with NGS readout

Olink Explore HT represents our most comprehensive solution, capable of measuring up to 3,000 proteins per sample. Olink Explore HT platform represents a significant advancement in high-throughput proteomics, offering expanded capabilities for protein biomarker discovery and analysis. This next-generation platform builds upon Olink's proprietary Proximity Extension Assay (PEA) technology, utilizing a dual recognition approach that ensures high specificity and negligible cross-reactivity. The technology employs matched pairs of antibodies linked to unique DNA sequences, allowing for protein detection only when both antibodies bind their target, effectively eliminating non-specific binding signals. Olink Explore HT — Olink®

High-throughput Next Generation Sequencing (NGS) platform
Measures up to 3,000 proteins per sample
Perfect for large-scale studies
Broadest protein coverage
Uses PEA technology with NGS readout

What makes all these platforms special is that they all use our proprietary PEA (Proximity Extension Assay) technology, which ensures exceptional specificity and sensitivity across all three platforms. The main differences lie in their throughput, protein coverage, and readout technology.

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